Peptide Research Center

Explore published peptide research explained in plain English.

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EmergingRandomized Trial2022

Tirzepatide SURMOUNT-1 Weight Loss Trial

A large phase 3 trial showing substantial weight loss with tirzepatide, a dual GLP-1/GIP agonist.

Tirzepatide · New England Journal of MedicineRead
Strong EvidenceReview2023

Semaglutide and Appetite Regulation

A mechanistic review of how GLP-1 receptor agonism affects central appetite signaling and food intake.

Semaglutide · Nature Reviews EndocrinologyRead
Strong EvidenceRandomized Trial2024

Retatrutide Phase 2 Trial Overview

A phase 2 trial reporting substantial weight loss with retatrutide, a triple GLP-1/GIP/glucagon agonist, in adults with obesity.

Retatrutide · New England Journal of MedicineRead
Strong EvidenceRandomized Trial2024

Cagrilintide + Semaglutide (CagriSema) Combination Concept

An overview of the CagriSema concept combining an amylin analog (cagrilintide) with a GLP-1 agonist (semaglutide).

Semaglutide + Cagrilintide · The LancetRead
Strong EvidenceReview2022

Thymosin Alpha-1 in Immune Modulation: A Review

A review of thymosin alpha-1's immune-modulating effects and its approved uses in several countries.

Thymosin Alpha-1 · Expert Review of Clinical ImmunologyRead
Strong EvidenceHuman2020

MK-677 (Ibutamoren) Effects on Sleep and IGF-1

A human study reporting MK-677 increased REM sleep and IGF-1 in healthy older adults.

MK-677 · SleepRead
Strong EvidenceRandomized Trial2019

Bremelanotide (PT-141) for Female Sexual Dysfunction

Pivotal trials behind an approved medication for premenopausal HSDD, a melanocortin agonist acting on arousal signaling.

PT-141 · Obstetrics & GynecologyRead
Moderate EvidenceReview2023

GHK-Cu in Dermal Remodeling and Wound Healing

A review of copper peptide GHK-Cu in dermal remodeling, collagen stimulation, and wound healing.

GHK-Cu · Journal of Cosmetic DermatologyRead
Moderate EvidenceReview2021

NAD+ in Aging Biology: A Mechanistic Review

A widely cited review of NAD+ decline with aging and its roles in sirtuin signaling and mitochondrial function.

NAD+ · ScienceRead
EmergingAnimal2022

BPC-157 and Tendon Repair in Animal Models

Preclinical evaluation of BPC-157 in tendon-to-bone healing models, suggesting improved tissue repair.

BPC-157 · Journal of Tissue EngineeringRead
EmergingAnimal2021

Thymosin Beta-4 and Cardiac Repair Models

Preclinical work suggesting thymosin beta-4 supports cardiac cell migration and repair after injury.

TB-500 / Thymosin Beta-4 · NatureRead
Moderate EvidenceHuman2019

Ipamorelin Growth-Hormone Release in Healthy Adults

An early human study characterizing ipamorelin as a selective GH secretagogue with limited cortisol and appetite effects.

Ipamorelin · European Journal of EndocrinologyRead
EmergingAnimal2015

MOTS-c and Metabolic Homeostasis in Mice

A landmark study identifying MOTS-c as a mitochondrial peptide regulating metabolic homeostasis via AMPK.

MOTS-c · Cell MetabolismRead
EmergingAnimal2022

KPV Anti-Inflammatory Effects in Animal Models

Preclinical evaluation of KPV showing anti-inflammatory effects in an inflammatory bowel model.

KPV · Pharmacological ResearchRead
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