Half-Life, Accumulation & Elimination
Adjust a peptide's half-life and dosing schedule to instantly see why some peptides accumulate, why steady state occurs, and why it can take multiple half-lives for a peptide to be mostly eliminated.
Interactive visualizer
Educational only — adjust to see how it changes accumulation.
Relative units for visualization.
How often a new dose is added.
Total span of the chart.
Labels only — does not change the model.
Not used in the model — shown for context only.
24 h
No published value (educational default)
≈ 5 days
~5 half-lives (≈97% reached)
≈ 6.7 days
~6.6 half-lives (<1% remains)
200
after a 100-unit dose
100
just before next dose
2.0×
every 1 day(s)
Elimination milestones (single dose)
1 days
1 half-lives
2 days
2 half-lives
3 days
3 half-lives
4 days
4 half-lives
5 days
5 half-lives
6.6 days
6.6 half-lives
Concentration over time
8 doses, every 1 day(s)Single-dose daily timeline
Single-dose decay — hover a day. The darker bar marks ~one half-life (≈50% remaining).
Understanding steady state
Because this peptide has a long half-life, each new dose is given before the previous dose has completely cleared. Over several doses the overlapping amounts rise until elimination balances intake — a relatively stable level called steady state. Steady state is usually reached after about 5 half-lives.
What half-life means
A half-life is the time it takes for half of the peptide in the body to be eliminated. After one half-life, 50% remains. After two, 25%. After three, 12.5% — and so on. Because only half is removed each step, small amounts can linger for many half-lives. Half-life never means the peptide is suddenly "gone."
Why peptides differ
Structure, size, and how the body breaks a peptide down set its half-life. Some last minutes; others persist for a week.
Why longer ones accumulate
When the next dose arrives before the previous one has cleared, amounts overlap and build up — until loss balances intake.
Why it's not "gone"
Each half-life only halves what's left. It can take 5–7 half-lives for a dose to fall below ~1–3% of its starting amount.
Did you know?
A peptide isn't completely eliminated after one half-life — each one removes only about half of what remains, so trace amounts can persist for several half-lives.
Educational visualization. This simulator demonstrates general pharmacokinetic concepts using published half-life values and simplified mathematical models. Individual absorption, metabolism, distribution, and elimination vary between people and products. This visualization is provided for educational purposes only and should not be used to determine personal dosing or treatment decisions.
Compare two peptides
See half-life, accumulation, washout, and steady state side by side.
≈ 4.9 weeks
≈ 6.5 weeks
3.4×
345 / 245
≈ 4.3 weeks
≈ 5.7 weeks
3.4×
341 / 241